Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Amino-1-propanol → [2-(3-Hydroxypropyl)amino-2-oxoethoxy]acetic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Amino-1-propanol | HCID 9086 | — |
| 반응물 | 1,4-Dioxane-2,6-dione | HCID 78232 | — |
| 반응물 | Methanesulfonate | HCID 85257 | — |
| 생성물 | [2-(3-Hydroxypropyl)amino-2-oxoethoxy]acetic acid | HCID 20558885 | — |
반응 단계
methanesulfonate by (a) reacting diglycolic anhydride and 3-aminopropanol to produce [2-(3-hydroxypropyl)amino-2-oxoethoxy]acetic acid, (b) heating to cyclize the latter to obtain 4-(3-hydroxypropyl)-3,5-dioxomorpholine, (c) esterifying the latter with methanesulfonyl chloride to produce 3-(3,5-dioxomorpholino)propyl methanesulfonate and (d) reacting the mesylate with 4-[bis(2-bromo-p-tolyl)methyl]piperidine.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04256891 |
| 출처 데이터셋 | uspto-grants-1981_03 |
| ORD ID | ord-98f30747ac314423a4756d58ce1a3a28 |
| 출처 메모 | uspto-grants-1981_03 |