Carbonic Acid → 6-Hydroxy-6-methyl-2-heptanone

HRID 1277577노트

반응식

[OH:1]C(O)=O.[CH3:5][C:6]1([CH2:14]C#N)[CH2:11][CH2:10][CH2:9][C:8](C)([CH3:12])[O:7]1>>[CH3:5][C:6]([OH:1])([CH2:11][CH2:10][CH2:9][C:8](=[O:7])[CH3:12])[CH3:14]

참가 물질

반응물 2

HCID 767Carbonic Acid

HCID 53971717HCID 53971717, 화합물

생성물 1

HCID 787626-Hydroxy-6-methyl-2-heptanone

실험 절차

Taking an overall evaluation of the second and third reaction (which simulate a plant operating with recycle but without recycling the hydroxyketone), a 2,6,6-trimethyl-2-cyanomethyltetrahydropyran yield of 52.9 mol % is obtained with respect to the 2-methyl-heptan-2-ol-6-one introduced into the reaction. As the hydroxyketone conversion during each test is about 80%, it is foreseeable that the overall pyran nitrile yield would rise to around 66 mol % if the unconverted hydroxyketone was also recycled.

후처리

customthird reaction (which

출처 및 근거

ORD 기록: ord-88849f01caa845768ee30c5903c13546
출처 데이터셋: uspto-grants-1981_07
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04278602

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