(4-Aminophenoxy)benzene → HCID 898756, 화합물

HRID 1277817노트

반응식

HRID 1277817 반응식
[O:1]([C:8]1[CH:13]=[CH:12][C:11]([NH2:14])=[CH:10][CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl[C:16]([O:18][CH2:19][CH3:20])=[O:17]>N1C=CC=CC=1>[O:1]([C:8]1[CH:9]=[CH:10][C:11]([NH:14][C:16](=[O:17])[O:18][CH2:19][CH3:20])=[CH:12][CH:13]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

참가 물질

4

반응물 2

HCID 8764(4-Aminophenoxy)benzeneHCID 10928Ethyl chloroformate

생성물 1

HCID 898756HCID 898756, 화합물

시약·촉매·용매 1

HCID 1049Pyridine용매

반응 조건

온도
4 °C

실험 절차

4-Phenoxybenzenamine (18.5 grams; 0.1 mole) and pyridine (50 ml) were charged into a glass reaction vessel fitted with a mechanical stirrer and thermometer and cooled to about 4° C. Ethyl chloroformate (13.5 grams; 0.125 mole) was added and the reaction stirred at about 4° C. for a period of about 30 minutes, stirring was then continued at room temperature for another 16 hours. Crystallization occured, whereupon the precipitate was filtered from the reaction medium, washed with water, and air dried to give the desired product ethyl (4-phenoxyphenyl)carbamate.

후처리

  1. customfitted with a mechanical stirrer
  2. stirringstirring
  3. waitwas then continued at room temperature for another 16 hours
  4. customCrystallization
  5. filtrationwas filtered from the reaction medium
  6. washwashed with water, and air
  7. customdried

출처 및 근거

ORD 기록
ord-dedada6beb2747c1afa74bb05f7578fb
출처 데이터셋
uspto-grants-1981_07
특허 번호
US04279637

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