2,2-Dimethoxyethylmethylamine → N-[4-(4-nitrophenoxy)-3-nitrophenyl]-N'-(2,2-dimethoxyethyl)-N'-methylurea

HRID 1277844노트

반응식

HRID 1277844 반응식
[N+:1]([C:4]1[CH:25]=[CH:24][C:7]([O:8][C:9]2[CH:14]=[CH:13][C:12]([NH:15][C:16](=[O:20])OCC)=[CH:11][C:10]=2[N+:21]([O-:23])=[O:22])=[CH:6][CH:5]=1)([O-:3])=[O:2].[CH3:26][O:27][CH:28]([O:32][CH3:33])[CH2:29][NH:30][CH3:31]>C1(C)C=CC=CC=1>[N+:1]([C:4]1[CH:25]=[CH:24][C:7]([O:8][C:9]2[CH:14]=[CH:13][C:12]([NH:15][C:16]([N:30]([CH2:29][CH:28]([O:32][CH3:33])[O:27][CH3:26])[CH3:31])=[O:20])=[CH:11][C:10]=2[N+:21]([O-:23])=[O:22])=[CH:6][CH:5]=1)([O-:3])=[O:2]

참가 물질

4

반응물 2

HCID 85032,2-DimethoxyethylmethylamineHCID 53855470Ethyl [4-(4-nitrophenoxy)-3-nitrophenyl]carbamate

생성물 1

HCID 23451783N-[4-(4-nitrophenoxy)-3-nitrophenyl]-N'-(2,2-dimethoxyethyl)-N'-methylurea

시약·촉매·용매 1

HCID 1140Toluene용매

실험 절차

Ethyl [4-(4-nitrophenoxy)-3-nitrophenyl]carbamate (0.1 mole) and toluene (100 ml) are charged into a glass reaction vessel fitted with a mechanical stirrer, thermometer and condenser. N-(2,2-dimethoxyethyl)methanamine (0.15 mole) is added to the vessel and the mixture is refluxed for 16 hours. Solvent is then removed by mild warming under reduced pressure to yield the desired product N-[4-(4-nitrophenoxy)-3-nitrophenyl]-N'-(2,2-dimethoxyethyl)-N'-methylurea.

후처리

  1. customfitted with a mechanical stirrer
  2. temperaturethe mixture is refluxed for 16 hours
  3. customSolvent is then removed
  4. temperatureby mild warming under reduced pressure

출처 및 근거

ORD 기록
ord-e37ae63485aa45368a49ec3f1f025f91
출처 데이터셋
uspto-grants-1981_07
특허 번호
US04279637

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