Pyridine → HCID 12922684, 화합물

HRID 1277916

반응식

HRID 1277916 반응식
[P:1](=[O:7])([NH2:6])([S:4][CH3:5])[O:2][CH3:3].N1C=CC=CC=1.Cl[S:15][N:16]([CH:23]([CH3:25])[CH3:24])[C:17](=[O:22])[O:18][CH2:19][CH2:20][CH3:21].Cl.N1C=CC=CC=1.S(Cl)Cl>C(Cl)Cl>[CH2:19]([O:18][C:17]([N:16]([CH:23]([CH3:24])[CH3:25])[S:15][NH:6][P:1](=[O:7])([S:4][CH3:5])[O:2][CH3:3])=[O:22])[CH2:20][CH3:21]

참가 물질

7

반응물 5

HCID 1049PyridineHCID 4096MethamidophosHCID 25353Sulfur dichloride2회HCID 10176127Pyridinium chlorideHCID 12922683HCID 12922683, 화합물

생성물 1

HCID 12922684HCID 12922684, 화합물

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

To a stirred mixture of 4.0 g (0.028 mol) O,S-dimethyl phosphoramidothioate, 2.2 g pyridine (0.028 mol) and 15 ml of anhydrous methylene chloride, chilled to 0°-5° C., was added dropwise 6.0 g (0.028 mol) propyl (chlorosulfenyl)(isopropyl)carbamate over a period of 15 minutes. Pyridine hydrochloride forms immediately during addition of the sulfenyl chloride. The reaction mixture was stirred for an additional half hour at room temperature after the addition of the sulfenyl chloride.

후처리

  1. temperaturechilled to 0°-5° C.

출처 및 근거

ORD 기록
ord-c35fd00e208c42c198d6462c8173f4f0
출처 데이터셋
uspto-grants-1981_07
특허 번호
US04279897

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