Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1,1,1,2-Tetrachloro-2,2-difluoroethane → 3,3-Dimethyl-4,6,6,7-tetrachloro-7,7-difluoroenanthic acid methyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1,1,1,2-Tetrachloro-2,2-difluoroethane | HCID 6426 | — |
| 반응물 | Benzoin | HCID 8400 | — |
| 반응물 | Dimethylamine, hydrochloride | HCID 10473 | — |
| 반응물 | Methyl 3,3-dimethyl-4-pentenoate | HCID 114129 | — |
| 용매 | Acetonitrile | HCID 6342 | — |
| 생성물 | 3,3-Dimethyl-4,6,6,7-tetrachloro-7,7-difluoroenanthic acid methyl ester | HCID 15575036 | — |
반응 단계
37.5 g of 3,3-dimethyl-4-pentenoic acid methyl ester, 102 g of 1,1,1,2-tetrachloro-2,2-difluoroethane, 22 g of acetonitrile, 325 mg of FeCl3.6H2O, 255 mg of benzoin and 200 mg of dimethylamine hydrochloride were heated to 100°-120° C. in a 250 ml VA autoclave under 6 bars of nitrogen for 7 hours. Distillation of the mixture gave 3,3-dimethyl-4,6,6,7-tetrachloro-7,7-difluoroenanthic acid methyl ester of boiling point 129°-134° C./0.7-0.9 m bar. Refractive index: nD20 =1.4680. ##STR8##
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04279923 |
| 출처 데이터셋 | uspto-grants-1981_07 |
| ORD ID | ord-8d9c87fbabdc48cfa957e9862b8938dc |
| 출처 메모 | uspto-grants-1981_07 |