Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Oxalic Acid → N,N-Dimethyl-5-[[[2-[(1-methylthio-2-nitroethenyl)amino]ethyl]thio]methyl]-2-furanmethanamine oxalate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Oxalic Acid | HCID 971 | — |
| 반응물 | 5-(((2-Aminoethyl)thio)methyl)-N,N-dimethyl-2-furanmethanamine | HCID 162203 | — |
| 반응물 | 1,1-Bis(methylsulfanyl)-2-nitroethane | HCID 12372264 | — |
| 용매 | 1,4-Dioxane | HCID 31275 | — |
| 생성물 | N,N-Dimethyl-5-[[[2-[(1-methylthio-2-nitroethenyl)amino]ethyl]thio]methyl]-2-furanmethanamine oxalate | HCID 70539027 | 99.4% |
반응 단계
A solution of 1,1-bis(methylthio)-2-nitroethane (19.8 g) and 5-[[(2-aminoethyl)thio]methyl]-N,N-dimethyl-2-furanmethanamine (6.42 g) in dry dioxan (120 ml) was heated at 80° C. for 6 hours. Oxalic acid (3.8 g) in dry dioxan (40 ml) was added and the crystalline solid which separated was filtered, washed with dioxan and dried to give the title compound (12.55 g) m.p. 140°-143° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04279911 |
| 출처 데이터셋 | uspto-grants-1981_07 |
| ORD ID | ord-9f864dffe3924553b53db590a22afe22 |
| 출처 메모 | uspto-grants-1981_07 |