Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethyl 4-nitrophenylacetate → 2-(alpha-Ethoxycarbonyl-4-nitrobenzylidene)-1-methylpyrrolidine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethyl 4-nitrophenylacetate | HCID 79517 | — |
| 반응물 | 2,2-Diethoxy-1-methylpyrrolidine | HCID 297308 | — |
| 용매 | Benzene | HCID 241 | — |
| 생성물 | 2-(alpha-Ethoxycarbonyl-4-nitrobenzylidene)-1-methylpyrrolidine | HCID 54519793 | — |
반응 단계
Boil 50 g of 4-nitrophenylacetic acid ethyl ester and 41.4 g of 2,2-diethoxy-1-methylpyrrolidine under reflux for 3 hours in 250 ml of benzene. Distil off the benzene before recrystallizing the resulting residue from diethyl ether/petroleum ether to obtain the title compound at a yield of 52.6 g (77% of theory) in the form of red crystals of m.p. 82° to 83°.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04279918 |
| 출처 데이터셋 | uspto-grants-1981_07 |
| ORD ID | ord-be52418171e1411985dd9643aa0b5774 |
| 출처 메모 | uspto-grants-1981_07 |