HCID 13186905, 화합물 → 4-[(1-Methylpyrrolidin-2-yl)methyl]aniline

HRID 1278046노트

반응식

HRID 1278046 반응식
[N+:1]([C:4]1[CH:16]=[CH:15][C:7]([CH2:8][CH:9]2[CH2:13][CH2:12][CH2:11][N:10]2[CH3:14])=[CH:6][CH:5]=1)([O-])=O>C(O)C.[Pt](=O)=O.[H][H]>[NH2:1][C:4]1[CH:16]=[CH:15][C:7]([CH2:8][CH:9]2[CH2:13][CH2:12][CH2:11][N:10]2[CH3:14])=[CH:6][CH:5]=1

참가 물질

4

반응물 1

HCID 13186905HCID 13186905, 화합물

생성물 1

HCID 131869044-[(1-Methylpyrrolidin-2-yl)methyl]aniline

시약·촉매·용매 2

HCID 178506448HCID 178506448, 화합물촉매HCID 702Ethanol용매

실험 절차

Hydrogenate 18 g of 2-(4-nitrobenzyl)-1-methylpyrrolidine in ethanol with 300 mg of platinum dioxide/hydrogen. Filter the catalyst from the reaction mixture, concentrate the latter and recrystallize the thus-produced residue from n-hexane to obtain the title compound at a yield of 12.7 g (82% of theory).

후처리

  1. filtrationFilter the catalyst from the reaction mixture
  2. concentrationconcentrate the latter and
  3. customrecrystallize the thus-produced residue from n-hexane

출처 및 근거

ORD 기록
ord-1cb7867abf4a4a23b6ea281998cc6f6b
출처 데이터셋
uspto-grants-1981_07
특허 번호
US04279918

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