4-Aminofuro[3,2-c]pyridine-2-carbonitrile → 4-Amino-2-(aminomethyl)furo[3,2-c]pyridine

반응식

[NH2:1][C:2]1[C:7]2[CH:8]=[C:9]([C:11]#[N:12])[O:10][C:6]=2[CH:5]=[CH:4][N:3]=1.NC1C2C(=CC=C(CN)C=2)C=CN=1>>[NH2:1][C:2]1[C:7]2[CH:8]=[C:9]([CH2:11][NH2:12])[O:10][C:6]=2[CH:5]=[CH:4][N:3]=1

참가 물질

반응물 2

HCID 226658084-Aminofuro[3,2-c]pyridine-2-carbonitrile

HCID 226658411-Amino-7-isoquinolinemethanamine

생성물 1

HCID 226657294-Amino-2-(aminomethyl)furo[3,2-c]pyridine

실험 절차

This compound was prepared from 4-amino-furo[3,2-c]pyridine-2-carbonitrile (5.7 g), using the procedure described for 1-amino-7-(aminomethyl)isoquinoline . Yield: 3.5 g (60%); yellow crystals; m.p. 142-144° C.; EI-MS: 163 (M+).

출처 및 근거

ORD 기록: ord-396c934111904227b28a3d06ff1ecb53
출처 데이터셋: uspto-grants-2002_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06444672B1

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