Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Isopropanol → 1-n-Propyl-1-phenyl-2-(3-sulfamoyl-4 chlorobenzoyl) hydrazine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Isopropanol | HCID 3776 | — |
| 반응물 | Sodium Bicarbonate | HCID 516892 | — |
| 반응물 | 3-(Aminosulfonyl)-4-chlorobenzoyl chloride | HCID 3017979 | — |
| 반응물 | 1-Phenyl-1-propylhydrazine | HCID 12327162 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 1-n-Propyl-1-phenyl-2-(3-sulfamoyl-4 chlorobenzoyl) hydrazine | HCID 15571499 | — |
반응 단계
A vigorously stirred mixture of 14.0 g (0.1 mol) 1-phenyl-1-n-propylhydrazine, 8.4 g (0.1 mol) sodium bicarbonate, and 100 ml isopropanol was chilled to 0°-5° C., 23 g (0.09 mol) 3-sulfamoyl-4-chlorobenzoyl chloride was added in one portion, and the reaction mixture was allowed to stir for several hours, gradually warming to room temperature. Dilution with water and refrigeration overnight yielded solid material which was collected and recrystallized from acetone/water, mp. 102° C. (d).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04258059 |
| 출처 데이터셋 | uspto-grants-1981_03 |
| ORD ID | ord-5ad3a84d3190480f938908c1fad147db |
| 출처 메모 | uspto-grants-1981_03 |