1-Bromooctadecane → N,N-Bis(2-Hydroxyethyl)-N'-Octadecyl-1,3-Propanediamine

HRID 127987

반응식

HRID 127987 반응식
[CH2:1](Br)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18].[NH2:20][CH2:21][CH2:22][CH2:23][N:24]([CH2:28][CH2:29][OH:30])[CH2:25][CH2:26][OH:27]>C(O)C1C=CC=CC=1>[OH:30][CH2:29][CH2:28][N:24]([CH2:25][CH2:26][OH:27])[CH2:23][CH2:22][CH2:21][NH:20][CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18]

참가 물질

4

반응물 2

HCID 82181-BromooctadecaneHCID 21088(3-Aminopropyl)diethanolamine

생성물 1

HCID 20433008N,N-Bis(2-Hydroxyethyl)-N'-Octadecyl-1,3-Propanediamine

시약·촉매·용매 1

HCID 244Benzyl Alcohol용매

실험 절차

A solution of octadecyl bromide (26.65 g., 80 mM.), N-(3-aminopropyl)diethanolamine (105 g., 640 mM.) and benzyl alcohol (120 ml.) is heated at 130° C. for twenty-three hours. The benzyl alcohol is removed in vacuo (0.1 mm. Hg, and 75° C.) and the residue taken up in methylene chloride (250 ml.). The methylene chloride solution is washed with aqueous sodium hydroxide (1 N) then with brine. It is dried (Na2SO4), concentrated, and distilled; b.p. 242°-246° C. at 0.1 mm Hg. The product is a waxy solid.

후처리

  1. customThe benzyl alcohol is removed in vacuo (0.1 mm. Hg, and 75° C.)
  2. washThe methylene chloride solution is washed with aqueous sodium hydroxide (1 N)
  3. dry with materialIt is dried (Na2SO4)
  4. concentrationconcentrated
  5. distillationdistilled

출처 및 근거

ORD 기록
ord-081cf7686d4640d89305cd2c85ebec99
출처 데이터셋
uspto-grants-1981_03
특허 번호
US04258061

연결된 노트

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