Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Trimethyl borate → 2,5-Dimethoxyphenylboronic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Trimethyl borate | HCID 8470 | — |
| 반응물 | Benzene, 2-bromo-1,4-dimethoxy- | HCID 91353 | — |
| 반응물 | 5-Fluoro-2-methoxyphenylboronic acid | HCID 2782673 | — |
| 반응물 | Butyllithium | HCID 178418339 | — |
| 생성물 | 2,5-Dimethoxyphenylboronic acid | HCID 2734342 | 99% |
반응 단계
This compound was prepared in a manner similar to that of 5-Fluoro-2-methoxyphenylboronic acid (EXAMPLE 107) from 1-bromo-2,5-dimethoxybenzene (2.00 mL, 13.3 mmol), n-BuLi (2.5 M in hexanes; 5.34 mL, 13.3 mmol), and trimethylborate (4.5 mL, 40 mmol) to afford 2.43 g (99%) of 2,5-dimethoxyphenylboronic acid which was used without further purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06448405B1 |
| 출처 데이터셋 | uspto-grants-2002_09 |
| ORD ID | ord-751b4c79d692484790fe287aa70cc713 |
| 출처 메모 | uspto-grants-2002_09 |