(Phenylmethoxy)acetaldehyde → (RS)-4-[1-(2-Benzyloxy-ethyl)-pyrrolidine-3-sulfonyl]-phenol

반응식

FC(F)(F)C(O)=O.[NH:8]1[CH2:12][CH2:11][CH:10]([S:13]([C:16]2[CH:21]=[CH:20][C:19]([OH:22])=[CH:18][CH:17]=2)(=[O:15])=[O:14])[CH2:9]1.[CH2:23]([O:30][CH2:31][CH:32]=O)[C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1>>[CH2:23]([O:30][CH2:31][CH2:32][N:8]1[CH2:12][CH2:11][CH:10]([S:13]([C:16]2[CH:21]=[CH:20][C:19]([OH:22])=[CH:18][CH:17]=2)(=[O:15])=[O:14])[CH2:9]1)[C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1

참가 물질

반응물 2

HCID 108989(Phenylmethoxy)acetaldehyde

HCID 18425771(RS)-4-(Pyrrolidine-3-sulfonyl)-phenol trifluoroacetic acid

생성물 1

HCID 18425854(RS)-4-[1-(2-Benzyloxy-ethyl)-pyrrolidine-3-sulfonyl]-phenol

실험 절차

The title compound, MS: m/e=362.2 (M+H+) was prepared from (RS)-4-(pyrrolidine-3-sulfonyl)-phenol trifluoroacetic acid salt and benzyloxyacetaldehyde.

출처 및 근거

ORD 기록: ord-a2028686e1464945957b6a45afeea816
출처 데이터셋: uspto-grants-2002_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06451819B2

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