2,2-Difluoro-4-phenylbutan-1-ol → HCID 69926483, 화합물

HRID 1280755노트

반응식

HRID 1280755 반응식
[F:1][C:2]([F:13])([CH2:5][CH2:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)[CH2:3]O.FC(F)(F)C(O)=O.[NH:21]1[CH2:25][CH2:24][C@@H:23]([S:26][C:27]2[CH:32]=[CH:31][C:30]([OH:33])=[CH:29][CH:28]=2)[CH2:22]1>>[F:1][C:2]([F:13])([CH2:5][CH2:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)[CH2:3][N:21]1[CH2:25][CH2:24][C@@H:23]([S:26][C:27]2[CH:32]=[CH:31][C:30]([OH:33])=[CH:29][CH:28]=2)[CH2:22]1

참가 물질

3

반응물 2

HCID 184257752,2-Difluoro-4-phenylbutan-1-olHCID 69924259HCID 69924259, 화합물

생성물 1

HCID 69926483HCID 69926483, 화합물

실험 절차

The title compound, MS: m/e=364.2 (M+H+) was prepared from 2,2-difluoro-4-phenyl-butan-1-ol and (3R)-4-(pyrrolidin-3-ylsulfanyl)-phenol trifluoroacetic acid.

출처 및 근거

ORD 기록
ord-1225129ec1594004a7004c42233cb079
출처 데이터셋
uspto-grants-2002_09
특허 번호
US06451819B2

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