Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Aminophenol → Phenol, 4-[[2-nitro-4-(trifluoromethyl)phenyl]amino]-
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Aminophenol | HCID 403 | — |
| 반응물 | 4-Chloro-alpha,alpha,alpha-trifluoro-3-nitrotoluene | HCID 8462 | — |
| 용매 | Isopropanol | HCID 3776 | — |
| 생성물 | Phenol, 4-[[2-nitro-4-(trifluoromethyl)phenyl]amino]- | HCID 4771887 | 94.5% |
반응 단계
6.0 g of p-aminophenol was dissolved in 60 ml of isopropyl alcohol. To the solution was added 6.0 g of 4-chloro-3-nitro-benzotrifluoride and the resulting solution was heated under reflux for 12 hours. After the reaction, the solvent was removed by distillation and the residue was dissolved in benzene. The resulting solution was filtered and the solvent was removed from the filtrate by distillation. Thus, 7.5 g of the desired product was obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04259105 |
| 출처 데이터셋 | uspto-grants-1981_03 |
| ORD ID | ord-6440437156744dc8be699e3c27fa2396 |
| 출처 메모 | uspto-grants-1981_03 |