HCID 69985555, 화합물 → HCID 69987371, 화합물
반응식
[Si]([O:18][C:19]1[CH:52]=[CH:51][C:22]([O:23][CH2:24][C@@H:25]([OH:50])[CH2:26][NH:27][CH2:28][CH2:29][C:30]2[CH:49]=[CH:48][C:33]([NH:34][CH:35]3[CH2:40][CH2:39][N:38]([C:41](=[O:47])[CH2:42][CH2:43][CH2:44][CH2:45][CH3:46])[CH2:37][CH2:36]3)=[CH:32][CH:31]=2)=[CH:21][CH:20]=1)(C(C)(C)C)(C1C=CC=CC=1)C1C=CC=CC=1>C(Cl)(Cl)Cl.CO>[OH:50][C@H:25]([CH2:24][O:23][C:22]1[CH:51]=[CH:52][C:19]([OH:18])=[CH:20][CH:21]=1)[CH2:26][NH:27][CH2:28][CH2:29][C:30]1[CH:49]=[CH:48][C:33]([NH:34][CH:35]2[CH2:40][CH2:39][N:38]([C:41](=[O:47])[CH2:42][CH2:43][CH2:44][CH2:45][CH3:46])[CH2:37][CH2:36]2)=[CH:32][CH:31]=1참가 물질
3
실험 절차
1-{4-[4-(2-{[(2S)-3-(4-{[tert-Butyl(diphenyl)silyl]oxy}phenoxy)-2-hydroxypropyl]-amino}ethyl)anilino]-1-piperidinyl}-1-hexanone (0.13 g, 0.168 mmol) was reacted according to Procedure H (eluant: 5:1 chloroform-methanol containing 1% ammonium hydroxide) to give the title compound (0.058 g, 0.120 mmol).
출처 및 근거
- ORD 기록
- ord-48c0294486b04194938f17564993ed6a
- 출처 데이터셋
- uspto-grants-2002_09