Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethyl 2-(4,5-difluoro-2-nitroanilino)benzo[b]thiophene-3-carboxylate → Ethyl 2-(2-amino-4,5-difluoroanilino)benzo[b]thiophene-3-carboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethyl 2-(4,5-difluoro-2-nitroanilino)benzo[b]thiophene-3-carboxylate | HCID 18422335 | — |
| 반응물 | HCID 178418361 | HCID 178418361 | — |
| 촉매 | HCID 178418390 | HCID 178418390 | — |
| 용매 | Ethyl Acetate | HCID 8857 | — |
| 생성물 | Ethyl 2-(2-amino-4,5-difluoroanilino)benzo[b]thiophene-3-carboxylate | HCID 18422150 | — |
반응 단계
In the same manner as in Starting Material Synthesis Example 19 and using ethyl 2-(4,5-difluoro-2-nitroanilino)benzo[b]thiophene-3-carboxylate, ethyl acetate, 10% palladium-carbon and hydrogen (60 atm kg/cm2), ethyl 2-(2-amino-4,5-difluoroanilino)benzo[b]thiophene-3-carboxylate is obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06455521B1 |
| 출처 데이터셋 | uspto-grants-2002_09 |
| ORD ID | ord-47b36bfa83ca42a5b3a0d0fee59e2925 |
| 출처 메모 | uspto-grants-2002_09 |