1-(Thiazol-2-yl)piperazine → HCID 54520201, 화합물

반응식

[S:1]1[CH:5]=[CH:4][N:3]=[C:2]1[N:6]1[CH2:11][CH2:10][NH:9][CH2:8][CH2:7]1.Cl[CH:13]([C:15]1[CH:20]=[CH:19][C:18]([CH2:21][NH:22][C:23](=[O:25])[CH3:24])=[CH:17][CH:16]=1)[CH3:14]>>[S:1]1[CH:5]=[CH:4][N:3]=[C:2]1[N:6]1[CH2:7][CH2:8][N:9]([CH:13]([C:15]2[CH:20]=[CH:19][C:18]([CH2:21][NH:22][C:23](=[O:25])[CH3:24])=[CH:17][CH:16]=2)[CH3:14])[CH2:10][CH2:11]1

참가 물질

반응물 2

HCID 9118061-(Thiazol-2-yl)piperazine

HCID 18423036N-(4-(1-chloroethyl)phenylmethyl)acetamide

생성물 1

HCID 54520201HCID 54520201, 화합물

실험 절차

By similar reaction and treatment to that in Example 1(5) using 1-(2-thiazolyl)piperazine instead of phenylpiperazine and N-(4-(1-chloroethyl)phenylmethyl)acetamide instead of N-(4-chloromethylphenylmethyl) acetamide, the title compound was obtained as a brown oil.

후처리

customBy similar reaction and treatment to that in Example

출처 및 근거

ORD 기록: ord-998262b40c5644dbb7449d54bbe42536
출처 데이터셋: uspto-grants-2002_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06455528B1

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