2-Amino-4,5,6,7-tetrahydrobenzothiazole → 4-Hydroxy-2-methyl-N-(4,5,6,7-tetrahydro-2-benzothiazolyl)-2H-[1] benzothieno [2,3-e]-1,2-thiazine-3-carboxamide-1,1-dioxide
반응식
[OH:1][C:2]1[C:7]2[S:8][C:9]3[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=3[C:6]=2[S:5](=[O:16])(=[O:15])[N:4]([CH3:17])[C:3]=1[C:18]([O:20]CCC)=O.[NH2:24][C:25]1[S:26][C:27]2[CH2:33][CH2:32][CH2:31][CH2:30][C:28]=2[N:29]=1>>[OH:1][C:2]1[C:7]2[S:8][C:9]3[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=3[C:6]=2[S:5](=[O:15])(=[O:16])[N:4]([CH3:17])[C:3]=1[C:18]([NH:24][C:25]1[S:26][C:27]2[CH2:33][CH2:32][CH2:31][CH2:30][C:28]=2[N:29]=1)=[O:20]참가 물질
3
반응물 2
생성물 1
실험 절차
Prepared analogous to Example 1 from propyl 4-hydroxy-2-methyl-2H-[1] benzothieno [2,3-e]-1,2-thiazine-3-carboxylate-1,1-dioxide and 2-amino-4,5,6,7-tetrahydrobenzothiazole with a yield of 58% of theory.
출처 및 근거
- ORD 기록