1-Iodonaphthalene → 5-Methyl-1-(1-naphthyl)-2-(1H)-pyridone

HRID 1283272

반응식

[CH3:1][C:2]1[CH:3]=[CH:4][C:5](=[O:8])[NH:6][CH:7]=1.I[C:10]1[C:19]2[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=2)[CH:13]=[CH:12][CH:11]=1.C(=O)([O-])[O-].[Na+].[Na+].C(=O)([O-])[O-].[K+].[K+]>>[CH3:1][C:2]1[CH:3]=[CH:4][C:5](=[O:8])[N:6]([C:18]2[C:19]3[C:14](=[CH:13][CH:12]=[CH:11][CH:10]=3)[CH:15]=[CH:16][CH:17]=2)[CH:7]=1

참가 물질

반응물 4

HCID 70041-Iodonaphthalene

HCID 10340Sodium Carbonate

HCID 11430Potassium Carbonate

HCID 704822-Hydroxy-5-methylpyridine

생성물 1

HCID 101985775-Methyl-1-(1-naphthyl)-2-(1H)-pyridone수율 68%

실험 절차

5-Methyl-1-(1-naphthyl)-2-(1H)-pyridone is prepared by the reaction of 5-methyl-2-(1H)-pyridone and α-iodonaphthalene following the procedure of Example 1 but substituting anhydrous sodium carbonate for the potassium carbonate; yield 68%.

출처 및 근거

ORD 기록: ord-302b1602c5b049b5bad94833a431c35b
출처 데이터셋: uspto-grants-1976_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US03974281

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