Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 3-Chloro-4-methoxybenzoyl chloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | Methyl 3-chloro-p-anisate | HCID 123469 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 3-Chloro-4-methoxybenzoyl chloride | HCID 4769299 | — |
반응 단계
A mixture of 10.4 g. (0.052 mol.) of 3-chloro-4-methoxybenzoic acid methyl ester and 3.5 g. (0.09 mol.) of sodium hydroxide in 150 ml. of water was refluxed for two hours. The reaction mixture was cooled and acidified with 10% aqueous hydrochloric acid to precipitate 3-chloro-4-methoxybenzoic acid, m.p. 199°-202°. The acid was refluxed with thionyl chloride as described in the procedure of Example 9 to give 3-chloro-4-methoxybenzoic acid chloride, m.p. 55°-57°.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US03975537 |
| 출처 데이터셋 | uspto-grants-1976_08 |
| ORD ID | ord-3d84c3f678a24b7e9b92c4cbcf018d63 |
| 출처 메모 | uspto-grants-1976_08 |