Pyridinium chloride → 2,2-Diethyl-6-hydroxy-4,5-dimethyl-1H-indene-1,3(2H)-dione

HRID 1283867노트

반응식

HRID 1283867 반응식
[CH2:1]([C:3]1([CH2:18][CH3:19])[C:11](=[O:12])[C:10]2[C:5](=[CH:6][C:7]([O:15]C)=[C:8]([CH3:14])[C:9]=2[CH3:13])[C:4]1=[O:17])[CH3:2].Cl.N1C=CC=CC=1>O>[CH2:18]([C:3]1([CH2:1][CH3:2])[C:11](=[O:12])[C:10]2[C:5](=[CH:6][C:7]([OH:15])=[C:8]([CH3:14])[C:9]=2[CH3:13])[C:4]1=[O:17])[CH3:19]

참가 물질

4

반응물 2

HCID 10176127Pyridinium chlorideHCID 215167892,2-Diethyl-4,5-dimethyl-6-methoxy-indan-1,3-dione

생성물 1

HCID 215167872,2-Diethyl-6-hydroxy-4,5-dimethyl-1H-indene-1,3(2H)-dione

시약·촉매·용매 1

HCID 962Water용매

반응 조건

온도
180 °C

실험 절차

A mixture of 2,2-diethyl-4,5-dimethyl-6-methoxy-indan-1,3-dione (5.5 g., 0.021 mole) and pyridine hydrochloride (50 g.) is heated at 180°C. for six hours then poured into water (1 l) affording 4.0 g. of 2,2-diethyl-4,5-dimethyl-6-hydroxy-indan-1,3-dione which melts at 141°-142°C. after recrystallization from methanol-water.

후처리

  1. customaffording 4.0 g
  2. customof 2,2-diethyl-4,5-dimethyl-6-hydroxy-indan-1,3-dione which melts at 141°-142°C. after recrystallization from methanol-water

출처 및 근거

ORD 기록
ord-cb5bc4d9687e4deeaa455dceb10a414c
출처 데이터셋
uspto-grants-1976_08
특허 번호
US03976681

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