Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Bis(Chloromethyl) Ether → 1-(Chloromethyl)-2-fluoro-3,4-dimethoxybenzene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Bis(Chloromethyl) Ether | HCID 10967 | — |
| 반응물 | 2-Fluoro-3,4-dimethoxybenzaldehyde | HCID 603588 | — |
| 반응물 | 1-Fluoro-2,3-dimethoxybenzene | HCID 2758979 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 생성물 | 1-(Chloromethyl)-2-fluoro-3,4-dimethoxybenzene | HCID 237411 | — |
반응 단계
The 2-fluoroveratraldehyde used as indicated above is prepared as follows: 3-fluoroveratrole is reacted with monochloromethyl ether in glacial acetic acid to give 2-fluoro-3,4-dimethoxybenzyl chloride which is treated with hexamethylenetetramine in chloroform followed by refluxing in 50% acetic acid to yield the 2-fluoroveratraldehyde.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US03976695 |
| 출처 데이터셋 | uspto-grants-1976_08 |
| ORD ID | ord-698568d1285144f38373b489a08d7a01 |
| 출처 메모 | uspto-grants-1976_08 |