Diazoethane → Ethyl 6-methoxymethyloxy-2-naphthyl-alpha-methylacetate

HRID 1284394노트

반응식

HRID 1284394 반응식
[CH3:1][O:2][CH2:3][O:4][C:5]1[CH:6]=[C:7]2[C:12](=[CH:13][CH:14]=1)[CH:11]=[C:10]([CH:15]([CH3:19])[C:16]([OH:18])=[O:17])[CH:9]=[CH:8]2.[N+](=[CH:22][CH3:23])=[N-]>C(OCC)C>[CH3:1][O:2][CH2:3][O:4][C:5]1[CH:6]=[C:7]2[C:12](=[CH:13][CH:14]=1)[CH:11]=[C:10]([CH:15]([CH3:19])[C:16]([O:18][CH2:22][CH3:23])=[O:17])[CH:9]=[CH:8]2

참가 물질

4

반응물 2

HCID 70695DiazoethaneHCID 203350726-Methoxymethyloxy-2-naphthyl-alpha-methylacetic acid

생성물 1

HCID 70589918Ethyl 6-methoxymethyloxy-2-naphthyl-alpha-methylacetate

시약·촉매·용매 1

HCID 3283Diethyl Ether용매2회

실험 절차

To a solution of 26 g. of 6-methoxymethyloxy-2-naphthyl-α-methylacetic acid and 500 ml. of diethyl ether are slowly added a solution comprising of 5.6 g. of diazoethane and 50 ml. of diethyl ether. The reaction mixture is allowed to stand for 15 minutes and then is evaporated under reduced pressure to yield ethyl 6-methoxymethyloxy-2-naphthyl-α-methylacetate. By replacing diazoethane with diazopropane in the above process, propyl 6-methoxymethyloxy-2-naphthyl-α-methylacetate is obtained.

후처리

  1. customis evaporated under reduced pressure

출처 및 근거

ORD 기록
ord-7e0b5dcf8b3040e28e7059fbb7909605
출처 데이터셋
uspto-grants-1976_08
특허 번호
US03978124

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