Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Oxalyl chloride → Benzeneacetyl chloride, 4-bromo-
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Oxalyl chloride | HCID 65578 | — |
| 반응물 | Benzeneacetic acid, 4-bromo- | HCID 74654 | — |
| 반응물 | 6-Bromo-2-tetralone | HCID 2733553 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | Benzeneacetyl chloride, 4-bromo- | HCID 181552 | — |
반응 단계
The synthesis of 6-bromo-2-tetralone is accomplished by dissolving 4-bromophenylacetic acid in methylene chloride and dimethyl formamide, under nitrogen. Oxalyl chloride is added and the mixture is stirred under a positive nitrogen atmosphere to produce the 4-bromo-phenylacetyl chloride, at a yield which typically is better than 99%.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05464762 |
| 출처 데이터셋 | uspto-grants-1995_11 |
| ORD ID | ord-76ffd24e304642158af2cc014d8e9207 |
| 출처 메모 | uspto-grants-1995_11 |