Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 128605생성일: 2026년 10월 26일
Diethyl (ethoxymethylene)malonate → Diethyl 2-(6-trifluoromethyl-2-pyridylaminomethylene)malonate
https://huagongshe.com/reaction/128605
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Diethyl (ethoxymethylene)malonate | HCID 6871 | — |
| 반응물 | 2-Amino-6-(trifluoromethyl)pyridine | HCID 821024 | — |
| 생성물 | Diethyl 2-(6-trifluoromethyl-2-pyridylaminomethylene)malonate | HCID 19374312 | — |
반응 단계
A mixture of 6-trifluoromethylpyridin-2-amine (17.2 g) and diethyl ethoxymethylenemalonate (22.9 g) was heated at 95° C., under vacuum for 8 hours. The mixture was cooled and diluted with petroleum ether b.p. 60°-80° C. (50 ml). The mixture was filtered and the residue was recrystallised from IMS to give diethyl 2-(6-trifluoromethyl-2-pyridylaminomethylene)malonate, m.p. 125°-128° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US05464781 |
|---|
| 출처 데이터셋 | uspto-grants-1995_11 |
|---|
| ORD ID | ord-2745d60f2e3c4211bec208894ff000c1 |
|---|
| 출처 메모 | uspto-grants-1995_11 |
|---|
