참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Methyl acetoacetate | HCID 7757 | — |
| 반응물 | Dimethylformamide dimethyl acetal | HCID 78373 | — |
| 생성물 | Methyl 2-((dimethylamino)methylene)-3-oxobutanoate | HCID 53395488 | 94% |
반응 단계
A solution of methyl acetoacetate (5.0 mL, 46.33 mmol) and N,N-dimethylformamide dimethylacetal (6.8 mL, 47.95 mmol) was heated to 80° C. for 2.3 h. At this time, the reaction was cooled to 25° C. and was then concentrated in vacuo to afford 2-dimethylaminomethylene-3-oxo-butyric acid methyl ester (7.43 g, 94%) as a red/black solid. This material was used without further purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07728029B2 |
|---|
| 출처 데이터셋 | uspto-grants-2010_06 |
|---|
| ORD ID | ord-7ab93d08bb4a4e4f9f6760fb3038c041 |
|---|
| 출처 메모 | uspto-grants-2010_06 |
|---|
