Hydrazine → alpha,alpha-Difluoro-beta-hydroxy-3-(4-pyridinyl)-propanoic acid, hydrazide

참여 물질

반응 단계

α,α-difluoro-β-hydroxy-3-(4-pyridinyl)-propanoic acid, hydrazide (50) was prepared in the manner described in Example 10 on a 20 mmol scale using ethyl α,α-difluoro-β-hydroxy-3-(4-pyridinyl)-propanoate and hydrazine to yield 2.7 g (62%) of product. This product was used immediately in the manner described in Example 51, below.

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