Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(1,1'-Biphenyl)-4-sulphonyl chloride → N-(4-Methyl-3-trifluoromethyl-5-isoxazolyl)-4-biphenylsulfonamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (1,1'-Biphenyl)-4-sulphonyl chloride | HCID 74192 | — |
| 반응물 | 4-Methyl-3-(trifluoromethyl)isoxazol-5-amine | HCID 15613878 | — |
| 생성물 | N-(4-Methyl-3-trifluoromethyl-5-isoxazolyl)-4-biphenylsulfonamide | HCID 15453174 | 78% |
반응 단계
N-(4-Methyl- 3-trifluoromethyl-5-isoxazolyl)-4-biphenylsulfonamide was prepared in the same manner as described in Example 2b from 5-amino-4-methyl-3-trifluoromethyl-isoxazole and 4-biphenylsulfonyl chloride in 78% yield. Purification was achieved by recrystallization from methanol/water to give a white solid, m.p. 139°-140° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05464853 |
| 출처 데이터셋 | uspto-grants-1995_11 |
| ORD ID | ord-4c73efb1315242f48afe96f8d56d0ff9 |
| 출처 메모 | uspto-grants-1995_11 |