Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetic Acid → 4-Thiazolidinone, 5-[(2,3-dimethoxyphenyl)methylene]-2-thioxo-
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetic Acid | HCID 176 | — |
| 반응물 | 2,3-Dimethoxybenzaldehyde | HCID 66581 | — |
| 반응물 | Sodium Acetate | HCID 517045 | — |
| 반응물 | Rhodanine | HCID 1201546 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 4-Thiazolidinone, 5-[(2,3-dimethoxyphenyl)methylene]-2-thioxo- | HCID 4602117 | 95.6% |
반응 단계
A mixture of 2,3-dimethoxybenzaldehyde (5.2 g, 30 mmoles), rhodanine (4.0 g, 29 mmoles), sodium acetate (8.4 g, 102 mmoles), and acetic acid (50 ml) is stirred under an inert atmosphere and heated to reflux. After 4 hours the mixture is stirred into water (250 ml) and the precipitate is filtered off, rinsed successively with water (3X), ethanol (2X), and ether (2X), and dried to afford the pure product (7.8 g), mp 268°-269° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05464856 |
| 출처 데이터셋 | uspto-grants-1995_11 |
| ORD ID | ord-2a1b9a28b05d49ec9b038ce22124b7f3 |
| 출처 메모 | uspto-grants-1995_11 |