Methyl isothiocyanate → 5-(4-tert-Butyloxycarbonylaminobutyl)-3-methyl-2-thiohydantoin

HRID 1287292

반응식

HRID 1287292 반응식
CO[C:3](=[O:18])[C@H:4]([CH2:6][CH2:7][CH2:8][CH2:9][NH:10][C:11]([O:13][C:14]([CH3:17])([CH3:16])[CH3:15])=[O:12])[NH2:5].[CH3:19][N:20]=[C:21]=[S:22]>>[C:14]([O:13][C:11]([NH:10][CH2:9][CH2:8][CH2:7][CH2:6][CH:4]1[NH:5][C:21](=[S:22])[N:20]([CH3:19])[C:3]1=[O:18])=[O:12])([CH3:15])([CH3:16])[CH3:17]

참가 물질

3

반응물 2

HCID 11167Methyl isothiocyanateHCID 7018776(S)-Methyl 2-amino-6-((tert-butoxycarbonyl)amino)hexanoate

생성물 1

HCID 215076805-(4-tert-Butyloxycarbonylaminobutyl)-3-methyl-2-thiohydantoin

실험 절차

Using an analogous procedure to Example 1 Nε-t-butyloxycarbonyl-L-lysine methyl ester may be reacted with methyl isothiocyanate to give the title compound.

출처 및 근거

ORD 기록
ord-d2413c6eb72640149f98efbe1fa3b0a4
출처 데이터셋
uspto-grants-1976_10
특허 번호
US03984430

연결된 노트

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