Ammonia → 3-Nitro-4-phenoxy-5-sulphamyl-benzamide

HRID 1287764노트

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HRID 1287764 반응식
[N+:1]([C:4]1[CH:5]=[C:6]([CH:10]=[C:11]([S:20](=[O:23])(=[O:22])[NH2:21])[C:12]=1[O:13][C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)[C:7](Cl)=[O:8])([O-:3])=[O:2].[NH3:24]>>[N+:1]([C:4]1[CH:5]=[C:6]([CH:10]=[C:11]([S:20](=[O:23])(=[O:22])[NH2:21])[C:12]=1[O:13][C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)[C:7]([NH2:24])=[O:8])([O-:3])=[O:2]

참가 물질

3

반응물 2

HCID 222AmmoniaHCID 215060353-Nitro-4-phenoxy-5-sulfamoylbenzoyl chloride

생성물 1

HCID 215060723-Nitro-4-phenoxy-5-sulphamyl-benzamide

실험 절차

3-Nitro-4-phenoxy-5-sulphamyl-benzoyl chloride (4 g) was added in portions to liquid ammonia (40 ml). Then excess of ammonia was distilled off, and the residue was triturated with water (50 ml). The precipitated 3-nitro-4-phenoxy-5-sulphamyl-benzamide was isolated by filtration and recrystallized twice from aqueous ethanol. After drying in vacuo, the compound was obtained with a melting point of 255°-256° C.

후처리

  1. distillationThen excess of ammonia was distilled off
  2. customthe residue was triturated with water (50 ml)

출처 및 근거

ORD 기록
ord-d0ea5c23c35743649b8494542e3ada0e
출처 데이터셋
uspto-grants-1976_10
특허 번호
US03985777

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