1-Benzyl-3-pyrrolidinone → 1-Benzyl-3-[2-(4,4-dimethyl-2-oxazolin-2-yl)phenyl]-3-hydroxypyrrolidine

HRID 1287905

반응식

HRID 1287905 반응식
[CH2:1]([N:8]1[CH2:12][CH2:11][C:10](=[O:13])[CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Br[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=1[C:21]1[O:22][CH2:23][C:24]([CH3:27])([CH3:26])[N:25]=1>>[CH2:1]([N:8]1[CH2:12][CH2:11][C:10]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=2[C:21]2[O:22][CH2:23][C:24]([CH3:27])([CH3:26])[N:25]=2)([OH:13])[CH2:9]1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

참가 물질

3

반응물 2

HCID 698901-Benzyl-3-pyrrolidinoneHCID 2892962-(2-Bromophenyl)-4,4-dimethyl-4,5-dihydro-1,3-oxazole

생성물 1

HCID 215068061-Benzyl-3-[2-(4,4-dimethyl-2-oxazolin-2-yl)phenyl]-3-hydroxypyrrolidine

실험 절차

Reaction of 1-benzyl-3-pyrrolidone and 2-(2-bromophenyl)-4,4-dimethyl-2-oxazoline by the method described in Example 1c provides 1-benzyl-3-[2-(4,4-dimethyl-2-oxazolin-2-yl)phenyl]-3-hydroxypyrrolidine as an oil.

출처 및 근거

ORD 기록
ord-54ab445e01b54f0e9ae8f1121e373f86
출처 데이터셋
uspto-grants-1976_10
특허 번호
US03985889

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