Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N-methylhydroxylamine hydrochloride → alpha-(1-Methyl-2-nitroimidazole-5-yl)-N-methylnitrone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N-methylhydroxylamine hydrochloride | HCID 77906 | — |
| 반응물 | 1-Methyl-2-nitro-1H-imidazole-5-carboxaldehyde | HCID 100390 | — |
| 반응물 | Sodium Bicarbonate | HCID 516892 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | alpha-(1-Methyl-2-nitroimidazole-5-yl)-N-methylnitrone | HCID 325650 | — |
반응 단계
A mixture of 0.250 g. of 1-methyl-2-nitro-5-imidazolecarboxaldehyde, 0.150 g. of N-methylhydroxylamine hydrochloride and 0.150 g. of sodium bicarbonate is refluxed in 80 ml. of anhydrous ethanol for 2 hours and after filtration is concentrated to small volume. The title compound crystallizes on cooling. Yield: 0.24 g, m.p. 208°-209° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US03987053 |
| 출처 데이터셋 | uspto-grants-1976_10 |
| ORD ID | ord-2752f34f108c41339ac7b1ed499c1c8c |
| 출처 메모 | uspto-grants-1976_10 |