반응식
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[NH:11][C:10](=S)[CH2:9][N:8]=[C:7]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)[C:6]=2[CH:19]=1.[C:20]([NH:25][NH2:26])(=O)[CH:21]([CH3:23])[CH3:22]>C(O)C>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[N:11]3[C:20]([CH:21]([CH3:23])[CH3:22])=[N:25][N:26]=[C:10]3[CH2:9][N:8]=[C:7]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)[C:6]=2[CH:19]=1참가 물질
4
반응 조건
- 온도
- 250 °C
실험 절차
In the manner given in Example 2, 7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepine-2-thione is heated in ethanol with isobutyric acid hydrazide and the resulting product heated to 250° C. to give 8-chloro-1-isopropyl-6-phenyl-4H-s-triazolo-[4,3-a][1,4]benzodiazepine.
출처 및 근거
- ORD 기록
- ord-d76fb7e2ece14c96841b404f3f7a4841
- 출처 데이터셋
- uspto-grants-1976_10
- 특허 번호
- US03987052
연결된 노트
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