Sodium ethoxide → HCID 21503525, 화합물

HRID 1288169노트

반응식

HRID 1288169 반응식
C(OC([N:6]1[CH2:20][CH2:19][C:18]2[C:9](=[N:10][C:11]3[CH:12]=[CH:13][CH:14]=[CH:15][C:16]=3[C:17]=2[CH3:21])[CH:8](Cl)[CH2:7]1)=O)C.[O-]CC.[Na+]>C(O)C>[CH3:21][C:17]1[C:16]2[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=2[N:10]=[C:9]2[CH:8]=[CH:7][NH:6][CH2:20][CH2:19][C:18]=12

참가 물질

4

반응물 2

HCID 2723922Sodium ethoxideHCID 54025343HCID 54025343, 화합물

생성물 1

HCID 21503525HCID 21503525, 화합물

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

A mixture of 3 gm (5.42 millimols) of 5-chloro-1,2,4,5-tetrahydro-11-methyl-3-azepino[4,5-b]quinoline-carboxylic acid ethyl ester, 45 millimols of sodium ethoxide and 150 ml of ethanol was boiled for 2 hours. After distilling off the ethanol, the residue was dissolved in water, the solution was extracted with chloroform, the extract was dried with sodium sulfate, the solvent was evaporated, and the residue was recrystallized from ether.

후처리

  1. distillationAfter distilling off the ethanol
  2. dissolutionthe residue was dissolved in water
  3. extractionthe solution was extracted with chloroform
  4. dry with materialthe extract was dried with sodium sulfate
  5. customthe solvent was evaporated
  6. customthe residue was recrystallized from ether

출처 및 근거

ORD 기록
ord-760affd583a44a6aa0922acbdbf17777
출처 데이터셋
uspto-grants-1976_10
특허 번호
US03987047

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