참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Formaldehyde | HCID 712 | — |
| 반응물 | 2-Amino-3-methylpyridine | HCID 15347 | — |
| 반응물 | HCID 178418385 | HCID 178418385 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 2-[(1-Benzotriazolyl)methyl]-3-methyl pyridine | HCID 19424225 | 33.4% |
반응 단계
A mixture of 2-amino-3-methylpyridine (43.28 g, 0.4 mol) and benzotriazole (47.65 g, 0.4 mol) in EtOH (500 mL) was treated over 5 minutes with formaldehyde (32.2 g of 37% solution, 0.4 mol). The mixture was stirred at 20° C. overnight, then cooled and filtered to give 2-[(1-benzotriazolyl)methyl]-3-methyl pyridine (30 g, 31%). A sample was crystallized from EtOH; mp 175°-177° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US05464861 |
|---|
| 출처 데이터셋 | uspto-grants-1995_11 |
|---|
| ORD ID | ord-1aaa672e8cf44501af3e7389bcc2b229 |
|---|
| 출처 메모 | uspto-grants-1995_11 |
|---|
