Bromine → 4-Amino-3-bromo-5-nitrobenzenesulfonamide

HRID 1288315노트

반응식

HRID 1288315 반응식
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([S:8]([NH2:11])(=[O:10])=[O:9])=[CH:4][C:3]=1[N+:12]([O-:14])=[O:13].[Br:15]Br>CO>[NH2:1][C:2]1[C:3]([N+:12]([O-:14])=[O:13])=[CH:4][C:5]([S:8]([NH2:11])(=[O:10])=[O:9])=[CH:6][C:7]=1[Br:15]

참가 물질

4

반응물 2

HCID 24408BromineHCID 27743884-Amino-3-nitrobenzene-1-sulfonamide

생성물 1

HCID 218864374-Amino-3-bromo-5-nitrobenzenesulfonamide

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

7.0 G. of 4-amino-3-nitrobenzenesulfonamide is suspended in 150 ml. of methanol at room temperature and brominated with 5.2 g. of liquid bromine added dropwise over 15 minutes. The reaction mixture is filtered and the solid material recrystallized from isopropanol affording 4-amino-3-bromo-5-nitrobenzenesulfonamide, m.p. 216°-218° C.

후처리

  1. customat room temperature
  2. filtrationThe reaction mixture is filtered
  3. customthe solid material recrystallized from isopropanol

출처 및 근거

ORD 기록
ord-1b64dce6cdc0486ba3f366677b06db41
출처 데이터셋
uspto-grants-1976_10
특허 번호
US03987199

반응 노트

불러오는 중…