Methanol, 1,1-diethoxy-, 1-acetate → 6-Methyl[1,2,4]triazolo[1,5-a][1,3,5]triazine-7(6h)-thione

HRID 1289796노트

반응식

HRID 1289796 반응식
[NH2:1][C:2]1[N:6]([C:7]([NH:9][CH3:10])=[S:8])[N:5]=[CH:4][N:3]=1.[C:11](OC(OCC)OCC)(=O)C>>[CH3:10][N:9]1[C:7](=[S:8])[N:6]2[N:5]=[CH:4][N:3]=[C:2]2[N:1]=[CH:11]1

참가 물질

3

반응물 2

HCID 84166Methanol, 1,1-diethoxy-, 1-acetateHCID 32648395-amino-N-methyl-1,2,4-triazole-1-carbothioamide

생성물 1

HCID 2866546-Methyl[1,2,4]triazolo[1,5-a][1,3,5]triazine-7(6h)-thione수율 88%

실험 절차

The synthesis method of Example 55 was applied. The compound (1.49 g) obtained in Example 29 and diethoxymethyl acetate (12 ml) were used as reagents. The mixture was reacted at 75° C. for 2 hours to give 1.39 g of white crystals (yield 88%). The crystals were subjected to recrystallization from acetone to give white crystals.

후처리

  1. customThe synthesis method of Example 55
  2. customThe mixture was reacted at 75° C. for 2 hours

출처 및 근거

ORD 기록
ord-4146b97b44e04cf2987c623a3440ef5f
출처 데이터셋
uspto-grants-1998_05
특허 번호
US05750545

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