Methanol, 1,1-diethoxy-, 1-acetate → 2-[(Dimethylaminomethylidene)amino]-6-methyl-1,2,4-triazolo[1,5-a]-1,3,5-triazine-7(6H)-thione

HRID 1289798노트

반응식

HRID 1289798 반응식
[NH2:1][C:2]1[N:6]([C:7]([NH:9][CH3:10])=[S:8])[N:5]=[C:4]([N:11]=[CH:12][N:13]([CH3:15])[CH3:14])[N:3]=1.[C:16](OC(OCC)OCC)(=O)C>>[CH3:15][N:13]([CH:12]=[N:11][C:4]1[N:3]=[C:2]2[N:1]=[CH:10][N:9]([CH3:16])[C:7](=[S:8])[N:6]2[N:5]=1)[CH3:14]

참가 물질

3

반응물 2

HCID 84166Methanol, 1,1-diethoxy-, 1-acetateHCID 867525445-Amino-3-[(dimethylaminomethylidene)amino]-1-[methylamino(thiocarbonyl)]-1H-1,2,4-triazole

생성물 1

HCID 867525462-[(Dimethylaminomethylidene)amino]-6-methyl-1,2,4-triazolo[1,5-a]-1,3,5-triazine-7(6H)-thione수율 56%

실험 절차

The synthesis method of Example 55 was applied. The compound (486 mg) obtained in Example 33 and diethoxymethyl acetate (5 ml) were used as reagents. The mixture was reacted at 95° C. for 2 hours to give 282 mg of pale-brown crystals (yield 56%).

후처리

  1. customThe synthesis method of Example 55
  2. customThe mixture was reacted at 95° C. for 2 hours

출처 및 근거

ORD 기록
ord-691622487f6947b78fa0f9de9897e094
출처 데이터셋
uspto-grants-1998_05
특허 번호
US05750545

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