Methanol, 1,1-diethoxy-, 1-acetate → 2-[(N-Benzylidene)amino]-6-methyl-1,2,4-triazolo[1,5-a]-1,3,5-triazine-7 (6H)-thione

반응식

[NH2:1][C:2]1[N:6]([C:7]([NH:9][CH3:10])=[S:8])[N:5]=[C:4]([N:11]=[CH:12][C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[N:3]=1.[C:19](OC(OCC)OCC)(=O)C>>[CH:12](=[N:11][C:4]1[N:3]=[C:2]2[N:1]=[CH:10][N:9]([CH3:19])[C:7](=[S:8])[N:6]2[N:5]=1)[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

참가 물질

반응물 2

HCID 84166Methanol, 1,1-diethoxy-, 1-acetate

HCID 443321545-Amino-3-[(N-benzylidene)amino]-1-[methylamino(thiocarbonyl)]-1H-1,2,4-triazole

생성물 1

HCID 867525482-[(N-Benzylidene)amino]-6-methyl-1,2,4-triazolo[1,5-a]-1,3,5-triazine-7 (6H)-thione수율 93%

실험 절차

The synthesis method of Example 55 was applied. The compound (783 mg) obtained in Example 37 and diethoxymethyl acetate (5 ml) were used as reagents. The mixture was reacted at 90° C. for 1.5 hours to give 757 mg of white powdery crystals (yield 93%).

후처리

customThe synthesis method of Example 55
customThe mixture was reacted at 90° C. for 1.5 hours

출처 및 근거

ORD 기록: ord-a8810adf3fba431d9f89cfd75ccdfe35
출처 데이터셋: uspto-grants-1998_05
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05750545

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