Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methane → HCID 178516151, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methane | HCID 297 | — |
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Phenylhydrazine | HCID 7516 | — |
| 반응물 | Ethyl 4,4,4-trifluoroacetoacetate | HCID 67793 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | HCID 178516151 | HCID 178516151 | 79.3% |
반응 단계
A mixture of 44 ml (0.3 mol) of ethyl trifluoroacetoacetate and 33 mL (335.4 mmol) of phenylhydrazine in 60 ml of methanol containing 6 ml of conc. HCl solution was refluxed with stirring for 1.5 hours. After adding activated charcoal with stirring, the hot mixture was filtered. The residue was washed with methanol (2×70 ml), diluted with water, and the resulting white solid was filtered. The solid was washed with hexane and dried to afford 54.3 g (79%) of 1-phenyl-3-trifluoromethyl-5-hydroxypyrazole as a pale solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05750550 |
| 출처 데이터셋 | uspto-grants-1998_05 |
| ORD ID | ord-98dfa323a2214946b4c50a2aed386206 |
| 출처 메모 | uspto-grants-1998_05 |