참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 2-Methylimidazo[1,2-a]pyridin-8-ol | HCID 820953 | — |
| 반응물 | 2-(2,6-Dichlorophenyl)ethyl methanesulfonate | HCID 15565622 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 8-[2-(2,6-Dichlorophenyl)ethyloxy]-2-methylimidazo[1,2-a]pyridine | HCID 18923336 | 23.4% |
반응 단계
A mixture of 8-hydroxy-2-methylimidazo[1,2-a]pyridine (296 mg), 1,3-dichloro-2-(2-mesyloxyethyl)benzene (645 mg) and potassium carbonate (828 mg) in N,N-dimethylformamide (12 ml) was stirred for 6 hours at 70° C. The mixture was treated according to a similar manner to that of Preparation 16 to give 8-[2-(2,6-dichlorophenyl)ethyloxy]-2-methylimidazo[1,2-a]pyridine (150 mg).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US05750699 |
|---|
| 출처 데이터셋 | uspto-grants-1998_05 |
|---|
| ORD ID | ord-e000f68925e64e869fe194b41ff6db91 |
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| 출처 메모 | uspto-grants-1998_05 |
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