Tetrafluorophthalonitrile → 1,4-Bis(3,4-dicyanotrifluorophenoxy)tetrafluorobenzene

HRID 1290245노트

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HRID 1290245 반응식
[F:1][C:2]1[C:3](F)=[C:4]([F:13])[C:5]([F:12])=[C:6]([C:10]#[N:11])[C:7]=1[C:8]#[N:9].[F:15][C:16]1[C:21]([OH:22])=[C:20]([F:23])[C:19]([F:24])=[C:18]([OH:25])[C:17]=1[F:26].[Na].[Na]>CN(C=O)C>[C:8]([C:7]1[C:2]([F:1])=[C:3]([C:4]([F:13])=[C:5]([F:12])[C:6]=1[C:10]#[N:11])[O:22][C:21]1[C:16]([F:15])=[C:17]([F:26])[C:18]([O:25][C:3]2[C:4]([F:13])=[C:5]([F:12])[C:6]([C:10]#[N:11])=[C:7]([C:8]#[N:9])[C:2]=2[F:1])=[C:19]([F:24])[C:20]=1[F:23])#[N:9]

참가 물질

4

반응물 2

HCID 74600TetrafluorophthalonitrileHCID 88247385Disodium tetrafluorohydroquinone

생성물 1

HCID 111459791,4-Bis(3,4-dicyanotrifluorophenoxy)tetrafluorobenzene수율 54%

시약·촉매·용매 1

HCID 6228Dimethylformamide용매

실험 절차

In an Erlenmeyer flask were charged 40.0 g (0.2 mol) of tetrafluorophthalonitrile and 0.1 liter of DMF. The flask containing the mixture was immersed in an ice-water bath to keep the mixture at 0° to 50° C. To the mixture was added portionwise in 10 minutes 11.3 g (0.05 mol) of disodium tetrafluorohydroquinone. The resulting mixture was stirred at that temperature for 20 minutes and then at room temperature for 30 minutes. Thereafter, the reaction mixture was treated in the same manner as in Example 16 and the product was identified in the same manner as in Example 16. Thus 14.6 g of 1,4-bis(3,4-dicyanotrifluorophenoxy)tetrafluorobenzene was obtained in a yield of 54%.

후처리

  1. additionThe flask containing the mixture
  2. customwas immersed in an ice-water bath
  3. customat 0° to 50° C
  4. waitat room temperature for 30 minutes
  5. additionThereafter, the reaction mixture was treated in the same manner as in Example 16

출처 및 근거

ORD 기록
ord-d2f0e041a766499880b67baece12a45b
출처 데이터셋
uspto-grants-1998_05
특허 번호
US05750731

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