Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Chloride → 5-Chloro-5,6,7,8-tetrahydroquinoline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Chloride | HCID 312 | — |
| 반응물 | 5,6,7,8-Tetrahydroquinolin-5-ol | HCID 4598923 | — |
| 생성물 | 5-Chloro-5,6,7,8-tetrahydroquinoline | HCID 18914103 | — |
반응 단계
5-Hydroxy-5,6,7,8-tetrahydroquinoline from step 1 above was converted to the chloride using the procedure as given in step 2 of Example 3. The crude 5-chloro-5,6,7,8-tetrahydroquinoline was purified by pressurized silica gel column chromatography using 7:3 EtOAc:hexane as eluant. 5-Chloro-5,6,7,8-tetrahydroquinoline was obtained as a pale yellow oil (TLC Rf = 0.40 (8:2 EtOAc:hexane)).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05756497 |
| 출처 데이터셋 | uspto-grants-1998_05 |
| ORD ID | ord-f398a21cbf54472fb39850596842c269 |
| 출처 메모 | uspto-grants-1998_05 |