Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetic Acid → N-Acetyl-L-proline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetic Acid | HCID 176 | — |
| 반응물 | Trifluoroacetic acid | HCID 6422 | — |
| 반응물 | Acetic Anhydride | HCID 7918 | — |
| 반응물 | Ammonium thiocyanate | HCID 15666 | — |
| 용매 | Triethylamine | HCID 8471 | — |
| 생성물 | N-Acetyl-L-proline | HCID 66141 | — |
반응 단계
ammonium thiocyanate (BDH, Analar), Aristar acetic acid (BDH), eptide synthesis grades of trifluoroacetic acid and acetic anhydride (Applied Biosystems) were used without further purification. Reagents for amino acid analysis of phenylthiocarbamyl amino acids were all of the highest possible purity (Inglis et al Biochem. Biophys. Methods 15:249, 1988). Pierce 6M constant boiling HC1 and Analar phenol (BDH) were used for hydrolysis and N,N-diisopropylethylamine (DIEA, Peptide Synthesis Grade, Applied Biosystems) replaced triethylamine in the drying reagent and in the coupling buffer.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05756667 |
| 출처 데이터셋 | uspto-grants-1998_05 |
| ORD ID | ord-34e412f94b714d90839c31b45566e546 |
| 출처 메모 | uspto-grants-1998_05 |