Water → 3-Hydroxy-N-benzimidazolon-5-yl-2-naphthamide

HRID 1292491노트

반응식

HRID 1292491 반응식
[OH:1][C:2]1[C:3]([C:12](Cl)=[O:13])=[CH:4][C:5]2[C:10]([CH:11]=1)=[CH:9][CH:8]=[CH:7][CH:6]=2.[NH2:15][C:16]1[CH:25]=[CH:24][C:19]2=[N:20][C:21](=[O:23])[N:22]=[C:18]2[CH:17]=1.O.C([O-])(=O)C.[Na+]>C1(C)C=CC=CC=1>[OH:1][C:2]1[C:3]([C:12]([NH:15][C:16]2[CH:25]=[CH:24][C:19]3=[N:20][C:21](=[O:23])[N:22]=[C:18]3[CH:17]=2)=[O:13])=[CH:4][C:5]2[C:10]([CH:11]=1)=[CH:9][CH:8]=[CH:7][CH:6]=2

참가 물질

6

반응물 4

HCID 962WaterHCID 517045Sodium AcetateHCID 128963863-Hydroxynaphthalene-2-carbonyl chlorideHCID 152505475-amino-2H-1,3-benzodiazol-2-one

생성물 1

HCID 204956833-Hydroxy-N-benzimidazolon-5-yl-2-naphthamide수율 86%

시약·촉매·용매 1

HCID 1140Toluene용매

실험 절차

CS 178560 describes the reaction of a solution of 3-hydroxy-2-naphthoyl chloride in toluene with 5-aminobenzimidazolone in the 30-fold amount of water in the presence of sodium acetate to give 3-hydroxy-N-benzimida-zolon-5-yl-2-naphthamide in 86% yield.

출처 및 근거

ORD 기록
ord-9b90926111044c6dbc82b2ffc0f95bdc
출처 데이터셋
uspto-grants-1998_05
특허 번호
US05756757

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