Ammonia → N-BENZYLIDENE-2-PROPYNYLAMINE

HRID 1292541노트

반응식

HRID 1292541 반응식
CS(O[CH2:6][C:7]#[CH:8])(=O)=O.[CH:9](=O)[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1.[NH3:17]>C1(C)C=CC=CC=1>[CH:9](=[N:17][CH2:6][C:7]#[CH:8])[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1

참가 물질

5

반응물 3

HCID 222AmmoniaHCID 240BenzaldehydeHCID 305925propargyl mesylate

생성물 1

HCID 4172560N-BENZYLIDENE-2-PROPYNYLAMINE수율 85%

시약·촉매·용매 1

HCID 1140Toluene용매

실험 절차

Propargyl methanesulfonate (31.6 g, 0.236 mol) and benzaldehyde (31.9 g, 0.3 mol) were dissolved in 103 g of toluene and an aqueous 28% ammonia solution (122 g, 2 mol) was added dropwise at 21° C. over 8 hours to the solution, followed by stirring at the same temperature for 15 hours. After separating, the resultant organic phase was washed with water and concentrated until the weight became 57.3 g to obtain a toluene solution containing 28.6 g (yield: 85%) of N-benzylidene-2-propynylamine.

후처리

  1. customAfter separating
  2. washthe resultant organic phase was washed with water
  3. concentrationconcentrated until the weight
  4. customto obtain a toluene solution

출처 및 근거

ORD 기록
ord-5ddd84546c0b4594a50cd7d2ef279fcb
출처 데이터셋
uspto-grants-1998_05
특허 번호
US05756769

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