Bromine → 2-Cyanobenzenesulfenyl bromide
반응식
C[S:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[C:9]#[N:10].[Br:11]Br>ClC1C=CC=CC=1>[C:9]([C:4]1[CH:5]=[CH:6][CH:7]=[CH:8][C:3]=1[S:2][Br:11])#[N:10]참가 물질
4
반응 조건
- 온도
- 100 °C
실험 절차
74.5 g (0.500 mol) of 2-cyanophenyl methyl sulfide and 250 g of chlorobenzene were placed in a 500 ml four-neck flask equipped with a stirrer, a thermometer, a dropping funnel and a condenser and 96.0 g (0.600 mol) of bromine was added dropwise thereto at about 100° C. over five hours while stirring. The excess bromine was removed with an aqueous sodium carbonate solution, followed by distillation under reduced pressure to obtain 90.4 g of 2-cyanobenzenesulfenyl bromide. The yield starting from 2-cyanophenyl methyl sulfide was 84.5%.
후처리
- customequipped with a stirrer
- customThe excess bromine was removed with an aqueous sodium carbonate solution
- distillationfollowed by distillation under reduced pressure
출처 및 근거
- ORD 기록
- ord-20bf5799bba44e31869a96c3e99008b6
- 출처 데이터셋
- uspto-grants-1998_05
- 특허 번호
- US05756806
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